Target Organ Toxicity : Volume 2, 1st Edition – FULL INSTANT DOWNLOAD | PDF DOCX EPUB

Name: Target Organ Toxicity : Volume 2
Edition: 1st Edition
ISBN-13: 9780367258719
ISBN-10: 0367258714
Addition ISBN: 9780429290299, 9781000694307, 9781000695847, 9780367258726, 100069738X, 9781000697384
Author(s): Gerald M. Cohen, Publisher: CRC Press, Copyright: 1986
First published in 1986: This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.